https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Precision dosing of targeted anticancer drugs-challenges in the real world https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31349 Thu 17 Feb 2022 09:28:34 AEDT ]]> Monte Carlo simulations of the clinical benefits from therapeutic drug monitoring of sunitinib in patients with gastrointestinal stromal tumours https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29616 1000). Conclusion: Although data from randomised clinical trials on the clinical impact of sunitinib TDM are lacking, our findings support implementation of sunitinib TDM in clinical practice. For rare cancers with well-defined exposure–response relationships, modelling and simulation might allow the optimisation of dosing strategies when clinical trials cannot be performed due to low number of patients.]]> Thu 03 Feb 2022 12:18:41 AEDT ]]> Wnt receptor gene FZD1 was associated with schizophrenia in genome-wide SNP analysis of the Australian Schizophrenia Research Bank cohort https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44131 Sat 08 Oct 2022 12:36:32 AEDT ]]>